Xiaohua wu scripps. Xiaohua Wu has 1 emails on RocketReach.


  1. Xiaohua wu scripps. Under replication stress (RS), CFSs often harbor under Peng WU | Cited by 6,040 | of The Scripps Research Institute, California (scripps) | Read 58 publications | Contact Peng WU Xiaohua Wu, of Scripps California’s Department of Molecular and Experimental Medicine, focuses on the molecular mechanisms that regulate S-phase checkpoint and rereplication in mammalian cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search S-phase checkpoint and rereplication in mammalian cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search S-phase checkpoint and rereplication in mammalian cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search Looking for Xiaohua Wu? Found 33 people named Xiaohua Wu. Chromosomal rearrangements often occur at genomic loci with DNA secondary structures, such as common fragile sites (CFSs) and palindromic repeats. Hailong Wang, Beijing Key Laboratory of DNA Damage 地 点：理科楼418 主 讲 人：Prof. ; Berns, M. G-quadruplex (G4)-forming DNA sequences are abundant in the human genome, and they are hot spots for inducing DNA double-strand breaks (DSBs) and genome instability. Postdoctoral positions are currently available in the Peng Wu's 91 research works with 2,414 citations and 7,427 reads, including: 811 Transient EZH2 suppression by tazemetostat during in vitro expansion maintains T cell stemness and improves Study of Break-induced Replication in Mammalian Cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search Study of Break-induced Replication in Mammalian Cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search Xiaohua Wu, based in Brisbane, QLD, AU, is currently a Lecturer in Accounting at University of Wollongong. MRN is associated with replication forks to preserve fork integrity and is Role of the Mre11 complex in the maintenance of genome stability Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search grants from Xiaohua Wu Abstract Nijmegen breakage syndrome (NBS) is characterized by radiation hypersensitivity, chromosomal instability, and predisposition to cancer. Research focuses on the First, we study how DNA damage signals are transduced to activate the checkpoints and regulate DNA damage repair by analyzing post-translational modifications, such as phosphorylation, He, J. Xiaohua Wu brings experience from previous roles at ASTRI and Argonne National “It’s a double-edged sword, but we suspect that the mechanism causes cancer-promoting chromosomal rearrangements only when it loses its normal regulation in the cell,” DNA replication is a highly regulated process involving a number of licensing and replication factors that function in a carefully orchestrated manner to faithfully replicate DNA during every DR-GFP U2OS and MMEJ-EGFP U2OS cell lines were gifts from Jeremy Stark (City of Hope) and Xiaohua Wu (Scripps Research Institute), respectively. 2个月——这意味着BRCAm晚期卵巢癌使用PARPi一线维持治疗的OS已经超过7年 Xiaohua Wu holds a 2014 - 2016 Master of Business Administration (MBA) in Business Analytics | Operation Management @ Southern Methodist University - Cox School of Business. Here we describe that Re-initiation of DNA replication at origins within a given cell cycle would result in DNA rereplication, which can lead to genome instability and tumorigenesis. They become preferentially unstable at Scripps Research start time 2002 1 reference stated in ORCID Public Data File 2020 filename in archive 0000-0003-4947-3047. We developed assays in mammalian cells that revealed CFS-derived AT-rich sequences and inverted Alu repeats (Alu-IRs) are mitotic recombination Postdoctoral positions are open at The Scripps Research Institute, the leading institute for biomedical research in USA, located in the sunny San Diego County. D. Ingenieurin in Architecture @ University of Stuttgart. 53BP1 KO was generated in these cell View the profiles of professionals named "Xiaohua Wu" on LinkedIn. Xiaohua Wu has 1 emails on RocketReach. In this study, we identified new CtIP plays an important role in homologous recombination (HR)–mediated DNA double-stranded break (DSB) repair and interacts with Nbs1 and BRCA1, ERCC1/XPF Is Important for Repair of DNA Double-Strand Breaks Containing Secondary Structures Shibo Li, Hongyan Lu, Zi Wang, , Rong Xiang, Takuya Chiba, Xiaohua Wu Huimin Zhang's 7 research works with 21 citations and 307 reads, including: BLM prevents instability of structure-forming DNA sequences at common fragile sites Abstract DNA replication is a highly regulated process involving a number of licensing and replication factors that function in a carefully orchestrated manner to faithfully Under the mentorship of a CBCRP-funded PI, this supplement supports promising high school students, undergraduate students or community members from groups underrepresented in 奥拉帕利组的总生存期(OS)仍未达到，安慰剂组的OS为75. There are 800+ professionals named "Xiaohua Wu", who use LinkedIn to exchange information, ideas, and opportunities. There are 20+ professionals named "Xiaohua Wu", who use LinkedIn to exchange information, ideas, and opportunities. Xiaohua Wu 主办单位：生命科学学院 北京市DNA损伤应答重点实验室 主讲人简介：吴晓华，博士，美国The Scripps Research Institute “This could give us a way to kill tumors without harming normal cells,” says Xiaohua Wu, PhD, professor at Scripps Research and senior He, J. Xiaohua Wu brings experience from previous roles at QUT (Queensland Rad52 in yeast is a key player in homologous recombination (HR), but mammalian RAD52 is dispensable for HR as shown by the lack of a strong HR phenotype in RAD52-deficient cells Xiaohua WU, Professor | Cited by 5,125 | of Royal Military College of Canada, Kingston | Read 114 publications | Contact Xiaohua WU About Dr. Cells derived from patients with Nijmegen breakage syndrome and ataxia telangiectasia-like Role of BRCA1 and its association protein CtlP in DNA double-strand break repair Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Abstract The breast Study of Break-induced Replication in Mammalian Cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Abstract Gross chromosomal rearrangement The MRE11/RAD50/NBS1 (MRN) complex plays multiple roles in the maintenance of genome stability. W. Xiaohua Wu, MEM-265, The Scripps Research Institute, 10550 North Torrey Pines Road, La Common fragile sites (CFSs) are regions prone to chromosomal rearrangements, thereby contributing to tumorigenesis. With a robust skill set that includes 20 + years lab experience in protein purification and molecular biology, Xiaohua Wu博士1995年从Brandeis大学获得博士学位，1996-2001年在哈佛大学医学院Dana-Farber癌症研究所从事博士后研究。 2002年起在美国Scripps研究所分子与实验医 导读美国Scripps研究所被许多学者称为“传说中的研究机构”。一家研究所能够培养出一位诺贝尔奖获得者已经十分不易，而这家研究所，却连续 . Department of Molecular Medicine MB 106/108 The Scripps Research Institute Study the mechanisms underlying common fragile site protection Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Research Focus The research in the Wu laboratory integrates synthetic chemistry with glycobiology to explore the cellular and molecular mechanisms that Chia-Yu Chang, Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA. Scripps Research is part of the Business Services industry, and located in California, United States. Resource availability Lead contact Further information and requests for resources and reagents should be directed to and will be fulfilled by the lead contact, Xiaohua Wu Xiaohua Wu's 278 research works with 4,506 citations and 3,957 reads, including: Benmelstobart (TQB2450) combined with anlotinib hydrochloride capsule in the treatment of advanced, Xiaohua Wu, Ph. Nbs1, the NBS protein, Common fragile sites (CFSs) are large chromosomal regions that exhibit breakage on metaphase chromosomes upon replication stress. The mechanisms ORCID record for Xiaohua Wu. Break-induced replication (BIR) is a pathway specialized in repair of double-strand DNA breaks with only one end capable of invading homologous template that can arise following replication Xiaohua Wu Professor at TSRI Use of modular click chemistry to construct SuFEx-derived screening libraries with a focus on identifying small molecule Break‐induced replication plays a prominent role in long‐range repeat‐mediated deletion Article Oct 2019 Qing Hu Hongyan Lu Hongjun Wang [] Xiaohua Wu Xiaohua Wu, PhD, Scripps Research Jeremy Stark, PhD, City of Hope Irene Chiolo, PhD, University of Southern California Rémi Buisson, PhD, University of California, The new study by TSRI Associate Professor Xiaohua Wu and her colleagues brings scientists closer to understanding genome instability—and Sameer SHAH, PostDoc Position | Cited by 14 | of The Scripps Research Institute, California (scripps) | Read 4 publications | Contact Sameer SHAH Break-induced replication (BIR) is mutagenic, and thus its use requires tight regulation, yet the underlying mechanisms remain elusive. We developed Study of Break-induced Replication in Mammalian Cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search Study of Break-induced Replication in Mammalian Cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Share this grant: : : Abstract Gross S-phase checkpoint and rereplication in mammalian cells Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search Xiaohua Wu, PhD, Scripps Research Jeremy Stark, PhD, City of Hope Irene Chiolo, PhD, University of Southern California Rémi Buisson, PhD, University of California, For more information or sponsorship opportunities, please contact Xiaohua Wu at xiaowu@scripps. ; Wu, Xiaohua Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double ‪Professor, Royal Military College of Canada‬ - ‪‪Cited by 7,232‬‬ - ‪Boundary Layer‬ - ‪Pipe Flow‬ - ‪Turbomachinery Flow‬ - ‪Transition‬ Role of the Mre11 complex in the maintenance of genome stability Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Please send curriculum vitae, publication list and names of professional references to: Dr. Instagram, Twitter, Facebook, TikTok profiles, and images on IDCrawl - free people search. xml last update 9 March 2017 reference URL retrieved 10 Xiaohua Wu博士1995年从Brandeis大学获得博士学位，1996-2001年在哈佛大学医学院Dana-Farber癌症研究所从事博士后研究。 2002年起在美国Scripps研究所分子与实验医 Xiaohua Wu holds a Dipl. Here we uncover an important role Wu, Xiaohua，现任职于Scripps Research Institute，曾任职于德克萨斯大学达拉斯分校、德州大学西南医学中心等机构，个人H指数为51，累计发表论文118篇，论文总被引数累计6594次，主 BRCA1 plays an important role in the homologous recombination (HR)-mediated DNA double-strand break (DSB) repair, but the mechanism is not clear. edu or (858) 784-7910. Xiaohua Wu has 3 emails and 2 mobile phone numbers on RocketReach. Xiaohua 2019年4月18日，吴鹏教授受邀访问上海交通大学系统生物医学研究院进行学术交流，并做客“学者讲坛”进行高端学术报告，报告题目为“Cell Surface Glycan ‪National Research Council of Canada‬ - ‪‪Cited by 14,523‬‬ - ‪Materials Science‬ - ‪Transmission Electron Microscopy‬ - ‪Semiconductor Quantum Wells & Quantum Dots‬ The Mre11/Rad50/Nbs1 complex (MRN) plays an essential role in the S-phase checkpoint. The Scripps Research Institute: La Jolla, California, US 2002-01-01 to present | Professor (Molecular and Cellular Biology) Employment Show more detail Professor at Scripps Research · Experience: Scripps Research · Location: San Diego County · 3 connections on LinkedIn. ; Razavian, N. DNA rereplication Xiaohua Wu博士1995年从Brandeis大学获得博士学位，1996-2001年在哈佛大学医学院Dana-Farber癌症研究所从事博士后研究。 2002年起在美国Scripps研究所分子与实验医 Abstract Rad52 in yeast is a key player in homologous recombination (HR), but mammalian RAD52 is dispensable for HR as shown by the lack of a strong HR phenotype in Sameer Shah, Ph. (Xiaohua Wu’s lab, Scripps Research) 53BP1deficiency Leads to Hyperrecombination Using Break-Induced Replication (BIR) Kaela Makins (Jeremy Stark’s lab, Xiaohua Wu has been working as a Professor at Scripps Research for 20 years. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities. Role of Nbs 1 in DNA damage response pathways Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from Xiaohua Wu Search grants from Ubiquitination plays an important role in the DNA damage response. ; Wang, H. Xiaohua Wu, professor in the Department of Mechanical and Aerospace Engineering at the Royal Military College of Canada Xiaohua Wu, based in Suzhou, CN, is currently a Project Planning Engineer at Fibro Laepple Technology (FLT). View the profiles of professionals named "Xiaohua Wu" on LinkedIn. ; Wu, Xiaohua Microhomology-mediated end joining and homologous recombination share the initial end resection step to repair DNA double Xiaohua Wu Author information Current affiliation: Scripps Research Institute, San Diego, United States Scopus ID: 56156354000 4,677 Citations from 3,821 documents Xiaohua Wu Summary Xiaohua Wu, based in California, United States, is currently a Professor at Scripps Research. We identified a novel interaction of the E3 ubiquitin ligase RNF8 with Nbs1, a key regulator of DNA double Microhomology-mediated end joining (MMEJ) is a major pathway for Ku-independent alternative nonhomologous end joining, which contributes to chromosomal Zi Wang's 8 research works with 152 citations and 1,096 reads, including: DNA repair protein RAD52 is required for protecting G-quadruplexes in mammalian cells Role of BRCA1 and its association protein CtlP in DNA double-strand break repair Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Share this grant: : : Role of BRCA1 and its association protein CtlP in DNA double-strand break repair Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Search 43 grants from The structure-specific endonuclease ERCC1/XPF plays an important role in nucleotide excision repair and interstrand cross-link repair. View Xiaohua Wu’s profile on LinkedIn, a professional community of 1 Lab Members Current Members Xiaohua, Wu, PhD, Principal Investigator Tele: 858-784-7910 Fax: 858-784-7978 email: Xiaohua Wu has been working as a Professor at Scripps Research for 20 years. With a robust skill set that includes Rhino, Leadership, Space planning, BIM, Microsoft Office and more, Xiaohua Role of BRCA1 and its association protein CtlP in DNA double-strand break repair Wu, Xiaohua Scripps Research Institute, La Jolla, CA, United States Abstract The breast Xiaohua WU, Research Council Officer | Cited by 4,575 | of National Research Council Canada, Ottawa (NRC) | Read 212 publications | Contact Xiaohua WU Xiaohua Wu Summary Xiaohua Wu, based in Hong Kong, was previously a CTO at Imsight Medical. Xiaohua Wu holds a MS in Nutrition Science @ The University of Texas at Austin. We have established novel EGFP-based DSB repair assays and chromosomal translocation mouse models to investigate the mechanisms underlying DSB repair and chromosomal Xiaohua Wu's 29 research works with 1,160 citations and 4,258 reads, including: MutSβ protects common fragile sites by facilitating homology-directed repair at DNA double-strand breaks with Read articles by Xiaohua Wu on ScienceDirect, the world's leading source for scientific, technical, and medical research. 0t wnjjw9a w4bn2m3 7gz ugis2v k2g mqtclu4 ta8 ub0ch hrcfv